The Royal Society of Chemistry
10 May 2005 - High Throughput Medicinal Chemistry

High throughput techniques have revolutionised the drug discovery process and are widely used in medicinal chemistry to speed the development of new and higher quality drug candidates. The scientific programme of the "High Throughput Medicinal Chemistry" meeting will include presentations on computational tools, purification of small organic molecules, ADME , fragment based design and case studies from GlaxoSmithKline, AstraZeneca and Merck Sharpe and Dohme.

Date: 10 May 2005
Location: Institute of Physics, 76 Portland Place, London
Application and Fees: RSC Members 112.00 inc VAT and Bank Charges, Non-RSC Members 153.00 inc VAT and Bank Charges, MNT Members 145.35 inc VAT and Bank Charges
For Further Information: Please contact Michele Sahrle.

Financial aid for students to attend is available. If you are interested in receiving financial aid, please contact Michele Sahrle


09:00 Registration and Coffee
09:50 Introduction
10:00 High Throughput Medicinal Chemistry - A Possible Computational Toolkit
Ashley George, GlaxoSmithKline
10:40 Evolution of Purification in Med Chem
Steve Jordan, CombiPure
11:20 Fragment Based Approaches to Medicinal Chemistry
Miles Congreve, Astex Technologies
12:00 Lunch
13:00 The Use of In Silico ADME Tools to Drive Good Library Design and Lead Optimisation
Mike Tarbit, Informatica
13:40 High Throughput Systems Based Research at GSK
Laramie Gaster, GlaxoSmithKline
14:20 Technology Enhanced Medicinal Chemistry: Development of Allosteric Akt Kinase Inhibitors
Craig Lindsley, Merck
15:00 Tea and Coffee
15:40 Recent Experiences in Hit-to-Lead
Sarah King, AstraZeneca
16:20 The Changing Face of Organic Synthesis
Steve Ley, University of Cambridge
17:00 Wine Reception
19:00 finish