High throughput techniques have revolutionised the drug discovery process and are widely used in medicinal chemistry to speed the development of new and higher quality drug candidates. The scientific programme of the "High Throughput Medicinal Chemistry" meeting will include presentations on computational tools, purification of small organic molecules, ADME , fragment based design and case studies from GlaxoSmithKline, AstraZeneca and Merck Sharpe and Dohme.

Date:	10 May 2005
Location:	Institute of Physics, 76 Portland Place, London
Application and Fees:	RSC Members £112.00 inc VAT and Bank Charges, Non-RSC Members £153.00 inc VAT and Bank Charges, MNT Members £145.35 inc VAT and Bank Charges
For Further Information:	Please contact Michele Sahrle. Financial aid for students to attend is available. If you are interested in receiving financial aid, please contact Michele Sahrle

	09:00 Registration and Coffee 09:50 Introduction 10:00 High Throughput Medicinal Chemistry - A Possible Computational Toolkit Ashley George, GlaxoSmithKline 10:40 Evolution of Purification in Med Chem Steve Jordan, CombiPure 11:20 Fragment Based Approaches to Medicinal Chemistry Miles Congreve, Astex Technologies 12:00 Lunch 13:00 The Use of In Silico ADME Tools to Drive Good Library Design and Lead Optimisation Mike Tarbit, Informatica 13:40 High Throughput Systems Based Research at GSK Laramie Gaster, GlaxoSmithKline 14:20 Technology Enhanced Medicinal Chemistry: Development of Allosteric Akt Kinase Inhibitors Craig Lindsley, Merck 15:00 Tea and Coffee 15:40 Recent Experiences in Hit-to-Lead Sarah King, AstraZeneca 16:20 The Changing Face of Organic Synthesis Steve Ley, University of Cambridge 17:00 Wine Reception 19:00 finish