The Royal Society of Chemistry
9 May 2006 - High Throughput Medicinal Chemistry

High throughput techniques have revolutionised the drug discovery process and are widely used in medicinal chemistry to speed the development of new and higher quality drug candidates. The scientific programme of the "High Throughput Medicinal Chemistry" meeting will include presentations on computational tools, purification of small organic molecules, ADME , fragment based design and case studies from GlaxoSmithKline, AstraZeneca and Merck Sharpe and Dohme.

Date: 9 May 2006
Location: Institute of Physics, 76 Portland Place, London
Application and Fees:
For Further Information: Please contact Michele Sahrle.

09:00 Registration and Coffee
09:50 Introduction
10:00 High Throughput Medicinal Chemistry - A Comparison of Computational Methods
Colin Edge, GlaxoSmithKline
10:40 Fluorous Mixture Synthesis Approaches to Natural Product Stereoisomer Libraries
Dennis Curran, University of Pittsburgh
11:20 Dealing From a Crooked Deck: The Card-Shark's Guide to High-Throughput Screening
Trevor Perrior, NCE Discovery
12:00 Lunch
13:00 The Application of High Throughput Technologies in Solid Form Development
Chris Frampton, Pharmorphix
13:40 Enabling HTS Hit Follow up via Chemoinformatics, File-Enrichment and Outsourcing
Graham Smith, Pfizer
14:20 Expedite Hit Discovery: Split & Pool in the 21st Century
Andreas Marzinzik, Novartis
15:00 Tea and Coffee
15:40 Agrochemical Lead Generation using Solid and Solution Phase HTS
Mike Robson, Syngenta
16:20 High Throughput Chemistry in Drug Discovery. Success or Sophistry?
Peter Machin, GlaxoSmithKline
17:00 Wine Reception
19:00 finish