The Royal Society of Chemistry
1st May 2007 - High Throughput Medicinal Chemistry



High throughput techniques have revolutionised the drug discovery process and are widely used in medicinal chemistry to speed the development of new and higher quality drug candidates. The scientific programme of the "High Throughput Medicinal Chemistry" meeting will include presentations on computational tools, purification of small organic molecules, ADME , fragment based design and case studies from GlaxoSmithKline, AstraZeneca and Merck Sharpe and Dohme.

Date: 1st May 2007
Location: SC1 auditorium, GlaxoSmithKline, Harlow
Application and Fees: RSC Members - 112.00, Non RSC Members - 153.00
For Further Information: Please contact Michele Sahrle.
 

09:00 Registration and Coffee
09:50 Introduction
10:00 Microwaves and Microreactors: New Faster Methods in Heterocyclic Chemistry
Mark Bagley, Cardiff University
10:40 The Application of High Throughput Chemistry in Discovery Research: Hope, Hype and Reality
Chris Hill, Organon
11:20 Asymmetric Catalysis: Simple and Easy!
Prof. Carsten Bolm, RWTH, Aachen University, Aachen, Germany
12:00 Tour of High Throughput Chemistry Facility and lunch
13:15 The Use of Combinatorial and Parallel Synthesis for Lead Identification and Optimisation
Brian McKittrick, Schering-Plough, NJ
13:55 Fragment based approaches to drug discovery
John Reader, Sareum Ltd
14:35 Design of Novel Matrix Metalloprotease Inhibitors - Classical Structure Based Design Using High Throughput Techniques
Ian Holmes, GSK
15:15 Tea and Coffee
15:40 Metalated Flatland Motifs for Pharmaceutical Research and Development
Prof. Victor Snieckus, Queen's University, Kingston, Canada
16:20 The Changing Face of Chemistry in Drug Discovery
David A Roberts, AstraZeneca
17:00 Close Meeting / Wine Reception
19:00 finish